이주련 (LEE, JULIAN)

연락처 CONTACT 전화 (PHONE): 02-820-0453
이메일 (e-mail): jul@ssu.ac.kr
연구 분야 RESEARCH INTEREST 생물물리학, 수리생물학, 시스템 생물학, 세포 내 동역학, 확률 과정, 비평형 통계물리
Biological Physics, Mathematical Biology, Systems Biology, Stochastic Processes, Subcellular dynamics, Nonequilibrium Statistical Physics
학력 EDUCATION 1994. 5 : 미국 브라운 대학교 물리학 박사 (고에너지 물리)
              Philosophy Doctor (High Energy Physics), Dept. of Physics, Brown University, USA 
1991. 5 : 미국 브라운 대학교 물리학 석사
              Science Master, Dept. of Physics, Brown University, USA
1989.8 : 서울대학교 물리학과 학사
              Bachelor, Dept. of Physics, Seoul National University
경력
CAREER
2015.3 -                 숭실대학교 의생명시스템학부 및 생명정보학과 교수
                              Professor, School of Systems Biomedical Science and Dept. of Bioinformatics and Life Science,
                              Soongsil University
2025.11 - 2026.8   미국 미네소타 대학교 물리학과 방문 연구자
                              Visiting Researcher, Dept. of Physics, University of Minnesota, USA
2018.9 - 2019.8     미국 아리조나 대학교 물리학과 및 생물물리학 센터 방문 연구자
                              Visiting Scholar, Dept. of Physics and Center for Biological Physics, Arizona State University, USA
2009.4 - 2015.2     숭실대학교 의생명시스템학부 및 생명정보학과 부교수
                              Associate Professor, School of Systems Biomedical Science and Dept. of Bioinformatics and Life Science,                                       Soongsil University
2010.3 - 2011.2     미국 캘리포니아 대학교 샌프란시스코 의약화학과 및 생물물리학 대학원 방문 부교수
                              Visiting Associate Professor, Dept. of Pharmaceutical Chemistry and Graduate Group in Biophysics,
                              University of California San Francisco, USA
2003.3 - 2009.3    숭실대학교 생명정보학과 조교수
                              Assistant Professor, Dept. of Bioinformatics and Life Science, Soongsil University
2003.2                  고등과학원 계산과학부 조교수
                              Assistant Professor, School of Computational Sciences, Korea Institute for Advanced Study
2001.7 - 2003.2    고등과학원 계산과학부 연구원
                             Research Fellow, School of Computational Sciences, Korea Institute for Advanced Study
2000.1 - 2001.6    일본 학술진흥재단 외국인 연구원 (동경 대학교)
                              Foreign Research Fellow, Japan Society for Promotion of Sciences (Univ. of Tokyo)
1998.1 - 1999.12  고등과학원 물리학부 연구원
                              Research Fellow, School of Physics, Korea Institute for Advanced Study
1997.6 - 1997.12   학술진흥재단 연구원 (한양 대학교)
                               Research Fellow, Korean Society for Promotion of Sciences (Hanyang Univ.)
1997.5                    아시아태평양 이론물리센터 방문연구자
                               Visiting Scholar, Asia-Pacific Center for Theoretical Physics
1994.6 - 1997.4     서울대학교 이론물리센터 연구원
                               Research Fellow, Center for Theretical Physics, Seoul National University

주요 논문 목록 PUBLICATION LIST (selected)

59. "Inference of causal interaction networks of gut microbiota using transfer entropy"
       Chanho Park, Junil Kim, and Julian Lee
       BMC Genomics 27 (2026) 28. (pdf)

58. "Identifying key drivers in a stochastic dynamical system through estimation of transfer entropy between univariate and
       multivariate time series"
       Julian Lee
       Physical Review E 111 (2025) 024308. (pdf)

57. "Poisson distributions in stochastic dynamics of gene expression: What events do they count? "
       Julian Lee
       Physica A 630 (2023) 129201. (pdf)

56. "Characterization of the common bed bug’s eggshell and egg glue proteins "
       Yeo Won Sim, Susie Cho, Si Hyeock Lee, Ju Hyeon Kim, Julian Lee (co-corresponding author), and SangYoun Park
       International Journal of Biological Macromolecules 249 (2023) 126004. (pdf)

55. "Few-body hydrodynamic interactions probed by optical trap pulling experiment "
       Julian Lee, Kyle Cotter, Ibrahim Elsadek, Matthew J Comstock, and Steve Pressé
       Journal of Chemical Physics 159 (2023) 024201. (pdf)

54. "Development of machine learning models based on molecular fingerprints for selection of small molecule inhibitors against
       JAK2 protein "
       Sharath Belenahalli Shekarappa, Shivananda Kandagalla, and Julian Lee
       Journal of Computational Chemistry 44 (2023) 1493. (pdf)

53. "In Silico Screening of Quorum Sensing Inhibitor Candidates Obtained by Chemical Similarity Search "
       Sharath Belenahalli Shekarappa, Hrvoje Rimac, and Julian Lee
       Molecules 27 (2022) 4887. (pdf)

52. "Use of D-galactose to regulate biofilm growth of oral streptococci "
       Eun-Ju Ryu, Sun-Jin An, Jaehyun Sim, Jun Sim, Julian Lee, and Bong-Hyu Choi
       Archives of Oral Biology 111 (2020) 104666. (pdf)

51. "Hydrodynamic interaction facilitates the unsteady transport of two neighboring vesicles "
      Julian Lee, Sean L. Seyler, and Steve Pressé
      Journal of Chemical Physics 151 (2019) 094108. (pdf)

50. "Quantitative Analysis of a Transient Dynamics of a Gene Regulatory Network"
      JaeJun Lee and Julian Lee
      Physical Review E 98 (2018) 062404. (pdf)

49. "Derivation of Markov processes that violate detailed balance"
      Julian Lee
      Physical Review E 97 (2018) 032110. (pdf)

48. "Transfer matrix algorithm for computing the exact partition function of a square lattice polymer"
      Julian Lee
      Computer Physics Communications 228 (2018) 11-21. (pdf)

47. "Stability analysis of an autocatalytic protein model"
      Julian Lee
      AIP advances 6 (2016) 055013. (link)

46. "Microcanonical analysis of a nonequilibrium phase transition"
      Julian Lee
      Physical Review E 93 (2016) 052148. (pdf)

45. "D-Galactose as an autoinducer 2 inhibitor to control the biofilm formation of periodontopathogens"
       Eun-Ju Ryu, Jaehyun Sim, Jun Sim, Julian Lee, and Bong-Kyu Choi
       Journal of Microbiology 54 (2016) 632. (pdf)

44. "Study on collapse and folding transitions of a lattice protein using exact enumeration"
      Jae Hwan Lee, Seung-Yeon Kim, and Julian Lee
      AIP advances 5 (2015) 127211. (link)

43. "Method for identification of rigid domains and hinge residues in proteins based on exhaustive enumeration"
      Jaehyun Sim, Jun Sim, Eunsung Park, and Julian Lee
      Proteins:Structure,Function,and Bioinformatics 83 (2015) 1054-1067. (pdf)

42. "Reply to C. Tsallis’«Conceptual Inadequacy of the Shore and Johnson Axioms for Wide Classes of Complex
      Systems»"
      Steve Pressé, Kingsuk Ghosh, Julian Lee, and Ken Dill
      Entropy 17 (2015) 5043-5046. (pdf)

41. "Single Molecule Conformational Memory Extraction: P5ab RNA Hairpin
      Steve Pressé, Jack Peterson, Julian Lee, Phillip Elms, Justin MacCallum, Susan Marqusee,
      Carlos Bustamante, and Ken Dill
      Journal of Physical Chemistry B 118 (2014) 6597-6603. (pdf)

40. "Nonadditive Entropies Yield Probability Distributions with Biases not Warranted by the Data"
     Steve Pressé, Kingshukl Ghosh, Julian Lee, and Ken Dill
      Physical Review Letters 111 (2013) 180604. (pdf)

39. "Exact Partition Function Zeros of the Wako-Saito-Muñoz-Eaton beta hairpin Model"
     Julian Lee
      Physical Review E 88 (2013) 022710.
     abstract    pdf

38. "Exact Partition Function Zeros of the Wako-Saito-Muñoz-Eaton Protein Model"
     Julian Lee
      Physical Review Letters 110 (2013) 248101.
     abstract    pdf

37. "Principles of maximum entropy and maximum caliber in statistical physics"
     Steve Pressé, Kingshukl Ghosh, Julian Lee, and Ken Dill
      Review of Modern Physics 85 (2013) 1115-1141.
     abstract   pdf

36. "Partition function zeros of a square-lattice homopolymer with nearest- and next-nearest-neighbor interactions"      Jae Hwan Lee, Seung-Yeon Kim and Julian Lee*
      Physical Review E 87 (2013) 052601.
     abstract    pdf

35. "Extracting Conformational Memory from Single-Molecule Kinetic Data"
     Steve Pressé, Julian Lee, and Ken Dill
      Journal of Physical Chemistry B 117 (2013) 495.
     abstract    pdf

34. "Microcanonical origin of the maximum entropy principle for open systems"
     Julian Lee* and Steve Pressé
      Physical Review E 86 (2012) 041126.
     abstract    pdf

33. "A derivation of the master equation from path entropy maximization"
     Julian Lee* and Steve Pressé
      Journal of Chemical Physics 137 (2012) 074103.
     abstract    pdf

32. "Exact partition function zeros of a polymer on a simple cubic lattice"
     Jae Hwan Lee, Seung-Yeon Kim, and Julian Lee*
      Physical Review E 86 (2012) 011802.
     abstract    pdf

31. "Collapse transition of a square-lattice polymer with next nearest-neighbor interaction "
     Jae Hwan Lee, Seung-Yeon Kim, and Julian Lee*
      Journal of Chemical Physics 135 (2011) 204102.
     abstract    pdf

30 . "The FALC-Loop web server for protein loop modeling"
     Junsu Ko, Dongseon Lee, Hahnbeom Park, Evangelos A. Coutsias, Julian Lee*, and Chaok Seok*
     Nucleic Acid Research 39 (2011) W210-W214.
     abstract    pdf   Server

29. "Refinement of protein termini in template-based modeling using conformational space annealing"
     Hahnbeom Park, Junsu Ko, Keehyung Joo, Julian Lee, Chaok Seok and Jooyoung Lee
     Proteins: Structure, Function, and Bioinformatics 79 (2011) 2725-2734.
     abstract    pdf

28. "Parallel Algorithm for Calculation of the Exact Partition Function of a Lattice Polymer"
     Jae Hwan Lee, Seung-Yeon Kim, and Julian Lee*
     Computer Physics Communications 182 (2011) 1027-1033.
     abstract    pdf

27. "Protein loop modeling by using fragment assembly and analytical loop closure"
     Julian Lee*, Dongseon Lee, Hahnbeom Park, Evangelos A. Coutsias, and Chaok Seok*
     Proteins: Structure, Function, and Bioinformatics 78 (2010) 3428-3436.
     abstract    pdf   Server

26. "Exact partition function zeros and the collapse transition of a two-dimensional lattice polymer"
     Jae Hwan Lee, Seung-Yeon Kim, and Julian Lee*
     Journal of Chemical Physics 133 (2010) 114106.
     abstract    pdf

25. "A new method for prediction of RNA secondary structure with pseudoknots, based on helix removal and refinement
     Bayarbaatar Amgalan and Julian Lee*
     Optimization 58 (2009) 861-869.
     abstract    pdf

24. "Protein Structure Prediction Using the Hybrid Energy Function, Fragment Assembly and Double Optimizaiton"
     Kwang-Hwi Cho
, Taek-Kyun Kim, and Julian Lee*
     J
ournal of the Korean Physical Society 52 (2008) 143-151.
     abstract    pdf

23. "Protein Loop Modeling Using Fragment Assembly "
     
Dongseon Lee, Chaok Seok*, and Julian Lee*
     J
ournal of the Korean Physical Society 52 (2008) 1137-1142.
     abstract    pdf

22. "Protein Folding Using Fragment Assembly and Physical Energy Function"
     Seung-Yeon Kim, Weontae Lee, and Julian Lee*
     Journal of Chemical Physics 125 (2006) 194908.

     abstract    pdf

21. "Measures for the assessment of fuzzy predictions of protein secondary structure",
     Julian Lee
     Proteins: Structure, Function, and Bioinformatics 65 (2006) 453-462.

     abstract    pdf

20. "Double Optimization for Design of Protein Energy Function",
     Seung-Yeon Kim, and Julian Lee*
     Lecture Notes in Bioinformatics 4115 (2006) 562
-570.
     abstract    pdf

19. "Fuzzy k-Nearest Neighbor Method for Protein Secondary Structure Prediction and its Parallel      Implementation",
     Seung-Yeon Kim, Jaehyun Sim, and Julian Lee*
     Lecture Notes in Bioinformatics 4115 (2006) 4
44-453.
     abstract    pdf

18. "Prediction of protein solvent accessibility using fuzzy k-nearest neighbor method"
     Jaehyun Sim, Seung-Yeon Kim, and Julian Lee*
     Bioinformatics 21< (2005)
2844-2849.
     abstract    pdf

17. " Protein structure prediction based on fragment assembly and beta-strand pairing energy function",
     Julian Lee, Seung-Yeon Kim, and Jooyoung Lee
     Journal of Korean Physical Society 46  (2005) 707 - 712.
     abstract    pdf

16. "Protein structure prediction based on fragment assembly and parameter optimization"
     Julian Lee, Seung-Yeon Kim, and Jooyoung Lee
     Biophysical Chemistry 115 (2005) 209-214.
     abstract    pdf

15. "Folding simulations of small proteins "
     Seung-Yeon Kim, Julian Lee, and Jooyoung Lee
     Biophysical Chemistry 115 (2005) 195-200.
     abstract    pdf

14. " Conformational space annealing and a lattice model protein "
     Julian Lee
     Journal of Korean Physical Society 45  (2004) 1450 - 1454.
     abstract    pdf

13. " Prediction of the secondary structure of proteins using PREDICT, a nearest neighbor method on pattern space"
     Keehyung Joo, Ilsoo Kim, Julian Lee, Seung-Yeon Kim, Sung Jong Lee, and Jooyoung Lee
     Journal of Korean Physical Society 45  (2004) 1441 - 1449.
     abstract    pdf

12. "Prediction of protein tertiary structure using PROFESY, a novel method based on fragment assembly and conformational space annealing"
     Julian Lee, Seung-Yeon Kim, Keehyung Joo, Ilsoo Kim, and Jooyoung Lee
     Proteins: Structure, Function, and Bioinformatics 56 (2004) 704-714.
     abstract    pdf

11. "Design of a protein potential energy landscape by parameter optimization"
    Julian Lee, Seung-Yeon Kim, and Jooyoung Lee

     Journal of Physical Chemistry B 108 (2004) 4525 - 4534.
     abstract    pdf 

10. "Folding of small proteins using a single continuous potential"
    Seung-Yeon Kim, Julian Lee, and Jooyoung Lee
    Journal of Chemical Physics 120 (2004) 8271 - 8276.
    abstract    pdf 

9. "Exact partition function zeros of two-dimensional lattice polymers"
    Julian Lee
   
Journal of Korean Physical Society 44  (2004) 617 - 620.
    abstract    pdf 

8. "Optimization of potential-energy parameters for folding of several proteins"
    Julian Lee, Seung-Yeon Kim, and Jooyoung Lee
    Journal of Korean Physical Society 44 (2004) 594 - 598.
    abstract    pdf 

7. "Profile-based nearest neighbor method for pattern recognition"
Keehyoung Joo, Julian Lee, Seung-Yeon Kim, Ilsoo Kim, Sung Jong Lee, and Jooyoung Lee
Journal of Korean Physical Society 44 (2004) 599 - 604.
abstract    pdf 

 

6. "Unbiased Global Optimization of Lennard-Jones Clusters for N>=201 Using the Conformational Space Annealing Method"
Julian Lee, In-Ho Lee, and Jooyoung Lee
Physical Review Letters 91 (2003) 080201-080204.
abstract    pdf 

 

5. "Prediction of protein tertiary structure using PROFESY, a novel method based on pattern matching and fragment assembly"
     Julian Lee, Seung-Yeon Kim, Keehyoung Joo, Ilsoo Kim, Saejoon Kim,  and Jooyoung Lee
     Fifth Meeting on the Critical Assessment of Techniques for Protein Structure Prediction (2002), p.A97 - A98.

 

4. "Prediction of protein secondary structure using PREDICT, a novel method based on pattern matching"
     Keehyoung Joo, Ilsoo Kim, Julian Lee, Seung-Yeon Kim, Sung Jong Lee, and Jooyoung Lee

      Fifth Meeting on the Critical Assessment of Techniques for Protein Structure Prediction (2002) p.A96 - A97.

 

3. "Full Optimization of Linear Parameters of a United Residue Protein Potential"
    Julian Lee, Kibeom Park, and Jooyoung Lee
    Journal of Physical Chemistry B 106
(2002) 11647.

 

2. "Tunneling between the giant gravitons in AdS5 x S5"
     Julian Lee
     
Physical Review D 64 (2001) 046012.

 

1. "Exact zeros of the partition function for a continuum system with  double Gaussian peaks"
     Julian Lee and Koo-Chul Lee
     
Physical Review E 62 (2000) p.4558.

board_a_back.gif board_a_home.gif